德莱兹测试是一个由美国食品药品监督管理局（FDA）的毒理学家 H·德莱兹（H. Draize）和雅各·M·史派斯（Jacob M. Spines）于1944年设计的急性毒性试验。这个实验最初用于测试化妆品，该过程包括将0.5毫升或0.5克测试物质抹到一只受限制但有意识的动物的眼睛或皮肤上一段时间，然后冲洗，并记录它的效果。这些动物会被观察长达14天，检测皮肤有否红斑和水肿，或发红、肿胀、出现分泌物、破溃、出血、眼睛有否混浊或失明。测试对象通常是白化兔，然而其他种类的动物也有使用，包括狗。如果测试造成该动物眼睛或皮肤不可逆的损伤，测试后动物会被安乐死。如果该产品测试的的动物没有永久性损伤，该动物可能重新用于测试。测试产品的所有痕迹从测试部位“洗掉”后，动物通常会再利用。

The Draize Test is an acute toxicity test devised in 1944 by Food and Drug Administration (FDA) toxicologists John H. Draize and Jacob M. Spines. Initially used for testing cosmetics, the procedure involves applying 0.5mL or 0.5g of a test substance to the eye or skin of a restrained, conscious animal, and then leaving it for set amount of time before rinsing it out and recording its effects. The animals are observed for up to 14 days for signs of erythema and edema in the skin test, and redness, swelling, discharge, ulceration, hemorrhaging, cloudiness, or blindness in the tested eye. The test subject is commonly an albino rabbit, though other species are used too, including dogs. The animals are euthanized after testing if the test renders irreversible damage to the eye or skin. Animals may be re-used for testing purposes if the product tested causes no permanent damage. Animals are typically reused after a "wash out" period during which all traces of the tested product are allowed to disperse from the test site.